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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASP1
All Species:
13.64
Human Site:
S222
Identified Species:
23.08
UniProt:
Q14847
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14847
NP_006139.1
261
29717
S222
A
A
D
E
D
E
V
S
F
Q
D
G
D
T
I
Chimpanzee
Pan troglodytes
XP_511445
391
42950
S352
A
A
D
E
D
E
V
S
F
Q
D
G
D
T
I
Rhesus Macaque
Macaca mulatta
XP_001085111
261
29741
S222
A
A
D
E
D
E
V
S
F
Q
D
G
D
T
I
Dog
Lupus familis
XP_851714
257
29048
S218
A
A
D
E
D
E
V
S
F
Q
D
G
D
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61792
263
29976
E222
Y
S
A
A
D
E
D
E
V
S
F
Q
D
G
D
Rat
Rattus norvegicus
Q99MZ8
263
29952
E222
Y
S
A
A
D
E
D
E
V
S
F
Q
D
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516545
118
13511
L80
R
L
K
Q
Q
S
E
L
Q
S
Q
V
R
Y
K
Chicken
Gallus gallus
Q01406
563
63311
V434
S
P
V
Y
Q
D
A
V
S
Y
D
A
E
S
A
Frog
Xenopus laevis
Q6GM14
376
42749
I336
Q
A
A
D
D
T
E
I
S
F
D
P
D
D
V
Zebra Danio
Brachydanio rerio
NP_997801
234
26681
F196
A
D
E
D
E
V
S
F
M
D
G
D
M
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I7C3
657
74228
Q222
T
L
P
P
P
P
I
Q
H
Q
Q
Y
N
T
A
Honey Bee
Apis mellifera
XP_001121584
320
35562
I222
T
N
P
P
T
R
K
I
G
S
V
A
D
I
D
Nematode Worm
Caenorhab. elegans
P34416
335
37006
D224
G
Y
L
K
A
Q
V
D
K
G
P
A
R
F
C
Sea Urchin
Strong. purpuratus
XP_797085
249
27176
F211
A
D
E
D
E
V
S
F
L
E
G
D
M
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.7
98.4
94.6
N.A.
95.4
96.1
N.A.
41.7
21.3
21.8
68.5
N.A.
23.1
42.1
37.3
50.1
Protein Similarity:
100
66.7
99.2
95.7
N.A.
97.3
97.3
N.A.
43.6
30.5
38
75.4
N.A.
30.4
53.4
51
60.5
P-Site Identity:
100
100
100
100
N.A.
20
20
N.A.
0
6.6
26.6
6.6
N.A.
13.3
6.6
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
6.6
33.3
40
33.3
N.A.
26.6
6.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
36
22
15
8
0
8
0
0
0
0
22
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
15
29
22
50
8
15
8
0
8
43
15
58
8
22
% D
% Glu:
0
0
15
29
15
43
15
15
0
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
29
8
15
0
0
8
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
8
15
29
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
15
0
0
0
0
0
22
36
% I
% Lys:
0
0
8
8
0
0
8
0
8
0
0
0
0
0
8
% K
% Leu:
0
15
8
0
0
0
0
8
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
15
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
15
15
8
8
0
0
0
0
8
8
0
0
0
% P
% Gln:
8
0
0
8
15
8
0
8
8
36
15
15
0
0
0
% Q
% Arg:
8
0
0
0
0
8
0
0
0
0
0
0
15
0
0
% R
% Ser:
8
15
0
0
0
8
15
29
15
29
0
0
0
8
0
% S
% Thr:
15
0
0
0
8
8
0
0
0
0
0
0
0
36
0
% T
% Val:
0
0
8
0
0
15
36
8
15
0
8
8
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
8
0
8
0
0
0
0
0
8
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _